Opportunity Information: Apply for CDC RFA CK22 2204
The US Public Health Pathogen Genomics Centers of Excellence (PGCoE) grant opportunity is a CDC-funded cooperative agreement designed to build a national network of centers that strengthen how the United States uses pathogen genomics and molecular epidemiology to prevent, detect, and respond to infectious disease threats. Run by the Department of Health and Human Services through the CDC (NCEZID), the program focuses on connecting academic expertise with public health practice so that cutting-edge genomic methods can be developed, tested, and then put into routine use across public health agencies. The overall purpose is practical: improve real-world outbreak detection and response by making genomic tools faster to adopt, easier to scale, and more usable in day-to-day public health work.
The program is built around a three-part strategy. First, it emphasizes accelerating the translation of pathogen genomic technologies and innovations into the US public health system, with a clear focus on supporting agencies at the local, state, tribal, territorial, and national levels. In other words, it is not just about research for its own sake; it is about taking proven genomic approaches (such as sequencing workflows, analysis pipelines, interpretation frameworks, and data-sharing practices) and helping them move into operational public health settings where they can guide decisions. Second, the opportunity prioritizes training and workforce development in microbial genomics and genomic epidemiology, aiming to expand the number of public health professionals who can generate, analyze, interpret, and apply genomic data during routine surveillance and outbreaks. Third, it targets rapid and scalable deployment of pathogen genomics during public health emergencies, so sequencing and genomic epidemiology can be used quickly to improve detection, characterization, and prevention of infectious disease threats when speed and scale matter most.
Administratively, this funding is offered as a discretionary cooperative agreement, meaning CDC expects substantial involvement and collaboration during the period of performance rather than simply issuing a grant with minimal federal interaction. The funding opportunity title is "US Public Health Pathogens Genomics Centers of Excellence," with Funding Opportunity Number CDC-RFA-CK22-2204 and CFDA number 93.084. Eligible applicants include state governments, county governments, city or township governments, and federally recognized Native American tribal governments, signaling that the program is intended to strengthen governmental public health capacity and infrastructure, often in partnership with academic or other technical collaborators. The CDC anticipated making about six awards under this announcement. The notice was created on March 18, 2022, with an original application closing date of May 18, 2022, and electronic submissions were due by 11:59 pm Eastern Time on the deadline date. The listing shows an award ceiling of 0, which typically indicates that applicants need to rely on the NOFO’s detailed budget guidance rather than a simple maximum amount shown in the summary field.
In practical terms, applicants were being asked to propose how they would operate as part of a coordinated national network that advances innovation in pathogen genomics while also ensuring those innovations translate into stronger public health action. This includes building pathways for adoption of new tools in public health laboratories and epidemiology programs, establishing training programs that can reach and upskill the workforce, and demonstrating the ability to surge genomic sequencing and analysis capacity during emergencies. The end goal is a more genomics-enabled public health system that can spot emerging threats sooner, track transmission more accurately, and support faster, better-targeted interventions.Apply for CDC RFA CK22 2204
- The Department of Health and Human Services, Centers for Disease Control - NCEZID in the health sector is offering a public funding opportunity titled "US Public Health Pathogens Genomics Centers of Excellence" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.084.
- This funding opportunity was created on Mar 18, 2022.
- Applicants must submit their applications by May 18, 2022 Electronically submitted applications must be submitted no later than 1159 pm ET on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 6 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Native American tribal governments (Federally recognized).
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